Beilstein J. Org. Chem.2018,14, 1859–1870, doi:10.3762/bjoc.14.160
their SCS analogues, SNSpincercomplexes are poorly studied for their use in coupling reactions. Accordingly, a series of water soluble cationic Pd(II) SNSpincercomplexes have been successfully synthesised and investigated in detail for their catalytic activity in Suzuki–Miyaura coupling reactions
investigation of the mechanism of the reaction revealed that a Pd(II) to Pd(IV) route is the more likely pathway which was further supported by computational studies.
Keywords: cationic palladium(II) complexes; Pd(II)/Pd(IV) complexes; SNSpincercomplexes; Suzuki–Miyaura; Introduction
The Suzuki–Miyaura C–C
, there are several examples of SCS-based palladium(II) complexes (1–13, Figure 1) which were reported to catalyse the Suzuki–Miyaura coupling reaction but the corresponding easy-to-synthesise SNSpincercomplexes are well underrepresented [33].
To the best of our knowledge, the only examples reported in
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Graphical Abstract
Figure 1:
Examples of reported SCS palladium(II) pincer complexes 1–13.